Some games that this issue occurs is Under One Wings, How to raise a wolf girl, onii kiss, and several others. This issue has been ongoing for a while and I have tried to troubleshoot this on my own. My mouse is wired and is brand new. Tried playing games on other computers gave me the same results. The only way I was able to play was on a machine with a different antivirus, however when disabling antivirus on an affected machine, the issue still persist.